— PLEXSO - Professional Organization
Dedicated to TPE in sepsis.
The literature organized. The protocols clarified.
Adult and pediatric. Peer-reviewed evidence. A vetted community of clinicians who run the protocols.
Curated evidence. Actionable at the bedside.
TPE research is scattered across critical care, hematology, and infectious disease literature. PLEXSO aggregates, screens, and organizes peer-reviewed data into a single specialty resource—no commercial filters, no editorial shortcuts.
Membership gives clinicians access to that curated base and direct contact with researchers running active protocols in adult and pediatric ICUs.
Three distinct knowledge channels
Adult Sepsis TPE
Pediatric Sepsis TPE
Member Blog
Protocol updates, clinical commentary, and field discussion authored by PLEXSO members between formal publications.
Curated publications on TPE in adult sepsis—screened for methodology, indexed by clinical question, and updated as new data clears peer review.
A discrete evidence base for PICU clinicians—pediatric dosing, volume parameters, and outcome data kept separate from adult literature.
Relevant for intensivists and transfusion medicine specialists managing adult critical illness.
Pediatric intensivists need a different evidence frame; this channel provides exactly that.
Expert-driven and current—the signal that keeps the community connected between journals.
A peer-governed body for a specific clinical problem.
Membership is open to clinicians and researchers working directly with TPE in sepsis. Access the literature, the protocols, and the people who developed them.